Anti-inflammatory effect of petroleum ether extract of Caesalpinia bonduc (L.) Roxb seed kernel in rats using carrageenan-induced paw edema
نویسندگان
چکیده
Petroleum ether extract of Caesalpinia bonduc L. (Roxb) seeds (Family: Caesalpiniaceae) was evaluated for its anti-inflammatory activity in rats. Wistar rats (120-150 g) of either sex were pretreated with petroleum ether extract of seed kernel of C. bonduc. Inflammation was induced in rat paw by injecting 0.1 ml of carrageenan (1% w/v) in subplantar region of right hind paw. Inflammation induced was significantly (p<0.05) decreased by petroleum ether extract of Caesalpinia bonduc (L.) Roxb seeds at dose level of 100 mg/kg is effective till 03 hour. The anti-inflammatory activity of petroleum ether extract of C. bonduc may be due to action of phytosterol.
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